产品货号:
Z32914
中文名称:
ABCC2抗体
英文名称:
Anti-ABCC2 Antibody
产品规格:
50μl|100μl|150μl
发货周期:
1~3天
产品价格:
询价
抗体名称 | Anti-ABCC2 Antibody |
指标别名 | ABC30;ABCC2;CMOAT;CMOAT1;cMRP;DJS;KIAA1010;MRP2 |
克隆性 | Monoclonal |
检验物种 | human |
应用范围 | WB,ICC/IF,FCM |
基因名称 | ABCC2 |
抗体来源 | Rabbit |
抗体类型 | IgG |
免疫原 | A synthesized peptide derived from human MRP2 |
实际分子量 | 170~250KD |
成分 | 500μg/mL;Rabbit IgG in phosphate buffered saline,pH7.4,150mM NaCl,0.02% sodium azide and 50% glycerol. |
纯化方式 | Affinity-chromatography |
浓度 | 500μg/mL |
产品形态 | 溶液 |
保存条件 | 12 months from date of receipt,-20℃ as supplied.6 months 2 to 8℃ after reconstitution.Avoid repeated freezing and thawing. |
背景资料 | Multidrug resistance-associated protein 2 (MRP2),also called canalicular multispecific organic anion transporter 1 (cMOAT) or ATP-binding cassette sub-family C member 2 (ABCC2),is a protein that in humans is encoded by the ABCC2 gene.The protein encoded by this gene is a member of the superfamily of ATP-binding cassette (ABC) transporters.ABC proteins transport various molecules across extra- and intra-cellular membranes.ABC genes are divided into seven distinct subfamilies (ABC1,MDR/TAP,MRP,ALD,OABP,GCN20,White).This protein is a member of the MRP subfamily which is involved in multi-drug resistance.This protein is expressed in the canalicular (apical) part of the hepatocyte and functions in biliary transport.Substrates include anticancer drugs such as vinblastine;therefore,this protein appears to contribute to drug resistance in mammalian cells.Several different mutations in this gene have been observed in patients with Dubin-Johnson syndrome (DJS),an autosomal recessive disorder characterized by conjugated hyperbilirubinemia. |
Uniprot ID | Q92887 |
基因名全称 | Canalicular multispecific organic anion transporter 1 |
推荐稀释比 | Western blot (WB) 1:500~2000 Immunocytochemistry/Immunofluorescence(ICC/IF) 1:20~100 Flow cytometry (FCM) 1:20 |
相关搜索:ABCC2抗体,ABCC2单抗,Anti-ABCC2 Antibody